Assessment of calorie free sweeteners and probiotics on oral health in children

Comparative analysis of the effect of calorie free sweeteners and probiotics on the oral microbial concentration in children: a randomised controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/074248

Enrollment

120

Registered

2024-09-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Intervention Group: Xylitol (So Sweet Xylitol Natural Sweetener, Sugar-Free), Aspartame (Sweet and Healthy Low-Calorie Aspartame-Based Sweetener), or Stevia (Magic Leaf Stevia Extract S

Eligibility

Inclusion criteria

Inclusion criteria: Children with no systemic diseases Children not currently taking antibiotics or other medications affecting oral health Children whose parents are willing for informed consent

Exclusion criteria

Exclusion criteria: Children with known allergies to probiotics or sweeteners Children with significant dental treatments within the past three months Children who do not consume more than 65% of the time frame (will be eliminated from the study group)

Design outcomes

Primary

Measure	Time frame
Oral microbial concentration assessed through saliva samplesTimepoint: Baseline - 1 hour after consumption, 1 week, 4 weeks	—

Secondary

Measure	Time frame
Gingival index Oral hygiene index (OHI) ICDASTimepoint: Baseline, 1 week, 4 weeks	—

Countries

India

Contacts

Public ContactDr Ramesh R

Saveetha Dental College and Hospital

rameshr.sdc@saveetha.com9895725236

Outcome results