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clinical study comparing the effects of two drugs Neostigmine and Sugammadex on heart rate and blood pressure in healthy patients undergoing nasal sinus surgeries

Comparing the effect of Neostigmine and Sugammadex on hemodynamic parameters in patients undergoing Functional Endoscopic Sinus Surgery - NIL

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/074213
Enrollment
112
Registered
2024-09-24
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Sugammadex: its a drug under classification of cyclodextrin, used to reverse steroidal non depolarizing muscle relaxant in general anesthesia. dose is 2mg/kg intravenously. the drug wil

Sponsors

Dr Moopens Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: healthy patients with no comorbidities. patients undergoing elective endoscopic nasal sinus surgeries.

Exclusion criteria

Exclusion criteria: patients with any other comorbidities. patients with cardiopulmonary , renal or hepatic impairments. patients with coagulation disorders. patients with history or ongoing drug abuse or alcohol abuse

Design outcomes

Primary

MeasureTime frame
to compare the effect of sugammadex and neostigmine on heart rate , blood pressure, mean arterial pressure, oxygen saturation, and QTc interval on ECG.Timepoint: every minute for first 10 minutes, every 10 minutes for first hour , hourly intervals for 24 hours.

Secondary

MeasureTime frame
to assess the incidence of reintubation. to assess any adverse effects like -anaphylactic reactions, post extubation stridor, post operative nausea vomiting.Timepoint: every hourly for 24 hours after the surgery

Countries

India

Contacts

Public ContactDr Abhishek R

Dr Moopens Medical College

shraddhakrupa27@gmail.com9243507325

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026