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to assess the effect of Melatonin in patients undergoing awake craniotomy

Effect of Melatonin Premedication in Patients Undergoing Awake Craniotomies: A Randomized Controlled Trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/074211
Enrollment
40
Registered
2024-09-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C71- Malignant neoplasm of brain Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Group M (Melatonin group): Patients will receive oral Tab Melatonin 5 mg on night before surgery and again two hours before surgery Control Intervention1: Group C (Control group): Patie

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients undergoing awake craniotomy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Patient Satisfaction Score measured on a 10-point Likert Scale ( 1 being the worst experience and 10 being the best ) Timepoint: one hour after surgery—

Secondary

MeasureTime frame
To assess the efficacy of oral melatonin premedication in decreasing preoperative anxiety in adult patients undergoing awake craniotomyTimepoint: one hour after surgery;To assess sleep quality on the night before surgeryTimepoint: morning of surgery;To determine the consumption of intraoperative dexmedetomidine and fentanyl Timepoint: At end of the surgery—

Countries

India

Contacts

Public ContactCharu Mahajan

AIIMS, New Delhi

charushrikul@gmail.com7042132730

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026