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Caffeine can decrease the oxygen therapy in preterm: a randomised control trial

Caffeine to decrease the oxygen support duration in moderate and late preterm a randomised control trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/074203
Enrollment
40
Registered
2024-09-24
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P220- Respiratory distress syndrome of newborn Health Condition 2: P285- Respiratory failure of newborn

Interventions

Intervention1: Early caffine therapy: caffine started to every moderate & late preterm neonate with persistant respiratory support for more than 6 hrs and continued till baby is off o2 support Control

Sponsors

Institute Neotia Getwel Healthcare Centre Dept of Neonatology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PMA: 320/7-36 6/7 weeks & PNA less than 14 days Requiring respiratory support (NPO2,NCPAP,HHHFNC,NIV) for more than 6 hours post birth.

Exclusion criteria

Exclusion criteria: Major congenital abnormality Renal or hepatic failure Arrythmias Babies requiring invasive MV within 6 hrs Caffeine received previously within 48 hours

Design outcomes

Primary

MeasureTime frame
Total duration of oxygen therapy Timepoint: at baseline,1 wk & 2 wk and at discharge

Secondary

MeasureTime frame
Anthropometry. Timepoint: At admission & Discharge;Feed Intolerance Requiring more than 12 Hrs Of Interruption Of Feed. Timepoint: any time prior to discharge;Frequency Of Intermittent HypoxiaTimepoint: at 1 wk& 2 wk &3 wk and at discharge;Hs PDA Requiring TreatmentTimepoint: any time prior to discharge;Prevalence of Retinopathy Of Prematurity, Bronchopulmonary Dysplasia, other respiratory Morbidity prior to dischargeTimepoint: any time prior to discharge

Countries

India

Contacts

Public ContactDr Aritra Ray

Neotia Getwel Healthcare Centre

aritraray.sunny1988@gmail.com9641632917

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026