Skip to content

A randomised controlled trial to compare the effectiveness of fentanyl with ropivacaine and dexmedetomidine with ropivacaine for epidural anaesthesia in lower limb orthopaedic surgeries

A comparative study of fentanyl with ropivacaine versus dexmedetomidine with ropivacaine for epidural anesthesia in lower limb orthopedic surgery : A randomized control trial study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/074201
Enrollment
80
Registered
2024-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: M218- Other specified acquired deformities of limbs

Interventions

Intervention1: Epidural Anaesthesia: Under aseptic precautions, skin wheal will be raised with 2% lignocaine, and lumbar epidural space will be identified with an 18G Tuohy needle using the loss of re

Sponsors

Agartala Government Medical College
Lead Sponsor
Department of Anaesthesiology
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: i.All patients who will be registered for lower limb orthopaedic surgeries and belonging to ASA (American Society of Anesthesiologists) grade I & II only. ii. Patients between 142 to 170 cms of height. iii. Patients who give valid informed written consent. iv. Patient with weight of 40-90 kgs. v. Patients with age between 18 years and 50 years

Exclusion criteria

Exclusion criteria: i. ASA Grade more then to III. ii. Known case of hypersensitive reactions to local anesthetics or adjuvants in the present study. iii. Patients with medical complications like anaemia, diabetes mellitus, cardiac disease, hypertension, chronic respiratory disease, hypovolemia, shock, septicemia, coagulation, abnormalities or in any anticoagulant therapy. iv. Patients with spinal deformity or vertebral anomaly. v. Local infection at the site of proposed puncture for epidural anesthesia. vi. Emergency surgeries.

Design outcomes

Primary

MeasureTime frame
i.Grades of sensory blockade. ii.Modified Bromage Scale for motor block . iii.The level of sedation will be assessed by modified Ramsay Sedation score.Timepoint: Grades of sensory blockade:assessed every 15 min for 1 hour Modified Bromage Scale for motor block:assessed 10 min after injection for 1 hour The level of sedation will be assessed by modified Ramsay Sedation score: assess every 5 mins for the first 30 minutes and then 15 minutes interval for the next 30 min and there after at 30 min interval for 120 minutes

Secondary

MeasureTime frame
1. To compare the postoperative block characteristics in both groups during the intra operative and post operative period. 2. To evaluate and compare the adverse effects intra-operatively and post-operatively in the two groups.Timepoint: 24 hour

Countries

India

Contacts

Public ContactDr Antu Datta

Agartala Government Medical college

drbiswajitsutradhar141@gmail.com9436459362

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026