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Studying B cell Activating Factor (BAFF) and Proliferation-Inducing Ligand (APRIL) Levels Before, During, and After Migraine Pain to Explore Possible Autoimmune Links

Evaluating The Role of B cell activating factor (BAFF) and proliferation-inducing ligand (APRIL) Levels in Migraine Phases to determine autoimmune Characteristics - Mig_BAFF

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/09/074182
Enrollment
45
Registered
2024-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G439- Migraine, unspecified

Interventions

Control Intervention1: Nil: Nil

Sponsors

AVICENCE Research Private Limited
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Migraine patients with and without aura Patients who are aged above 18 years

Exclusion criteria

Exclusion criteria: 1.Patients with additional comorbidity conditions were not allowed to participate. 2.Patients who have recently taken any immunosuppressants 3.Pregnant women were excluded 4.Patients with previous head injury

Design outcomes

Primary

MeasureTime frame
Quantification of BAFF and APRIL levels in different phases of migraineTimepoint: BAFF and APRIL levels will be quantified at specific time points during the pre-ictal, ictal, and post-ictal phases of a migraine. However, the exact timing of these phases may vary based on the development of migraine pain in each patient, so precise time points cannot be assured.—

Secondary

MeasureTime frame
Not ApplicableTimepoint: Not applicable—

Countries

India

Contacts

Public ContactNisha Smitha S

Sri Ramachandra Institute of Higher Education and Research (DU)

murugesan.a@sriramachandra.edu.in8870151588

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026