Comparison of the efficacy of two modes of administration of dexamethasone which include twin mix LA and submucosal injection in the intraoperative and postoperative outcome during mandibular third molar surgery

Evaluating the Efficacy of Twin Mixed Local Anaesthesia and Local Anaesthesia with Submucosal Dexamethasone Injection in Mandibular Third Molar Surgery – Prospective Comparative Clinical Trial - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/074172

Enrollment

Registered

2024-09-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: TWIN MIX LOCAL ANESTHESIA: (1.8ml of 2% lignocaine containing 1:200000 adrenaline + 1 ml of 4mg dexamethasone as a single injection for inferior alveolar nerve block given once Control

Eligibility

Inclusion criteria

Inclusion criteria: Subjects above the age of 21 with mesioangular impacted mandibular third molar of Pell & Gregory Class-I, Level A. Subjects who are in good physical status. Subjects who could understand and are willing to take part in the study and likely to comply with all study procedures

Exclusion criteria

Exclusion criteria: Refusal to participate in the study. Pregnancy and lactation. Patient having systemic disorder like diabetes, hypertension, cardiac or neurological disorder. Patients with reduced mouth opening (mouth opening above 30mm was considered normal) Patient with history of drug allergy to lignocaine, dexamethasone, amoxicillin, metronidazole, diclofenac. Patients with active infection. Patient under any antibiotics or analgesics coverage. Patient other than Pell & Gregory Class-I Level A. Patients with severe oral manifestations of systemic disease. Psychologic or psychiatric conditions that could influence response to treatment.

Design outcomes

Primary

Measure	Time frame
POST OPERATIVE PAIN, FACIAL SWELLING AND MOUTH OPENINGTimepoint: 7 days	—

Secondary

Measure	Time frame
INTRAOPERATIVE PAINTimepoint: 3 HOURS;POST OPERATIVE PAIN, FACIAL SWELLING AND MOUTH OPENINGTimepoint: 3rd day, 7th day	—

Countries

India

Contacts

Public ContactKarthiga M

Sri Balaji Vidyapeeth

dr.raghuk@gmail.com

Outcome results