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A Study on post operative pain management in patients undergoing Total Knee Replacement

Effect of Intravenous Dexmedetomidine in patients undergoing Total Knee Arthroplasty on post operative analgesic requirement - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/074147
Enrollment
50
Registered
2024-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Control Intervention1: Control (Group C): Total Participants: 25 This group of patients undergoing unilateral total knee replacement under spinal anaesthesia will not receive dexemedetomidine. Control

Sponsors

Kasturba Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adults aged 55-80 years. 2. Patients with ASA-PS I and II. 3. Unilateral total knee replacement.

Exclusion criteria

Exclusion criteria: 1.Not willing to participate in the study 2.ASA-PS III and above 3.Patients with severe pulmonary, hepatic, cardiac or renal disease 4.Total Knee Replacement under general anaesthesia 5.History of any drug allergies. 6.Psychiatric illness 7.Patients with an abnormal coagulation profile

Design outcomes

Primary

MeasureTime frame
Post operative anlagesic requirementTimepoint: 0,2,4,6,12 and 24 hours post surgery—

Secondary

MeasureTime frame
1.Hemodynamic variables 2.Time of supplementation of first rescue analgesia 3.Total intraoperavtive blood loss calculationTimepoint: preoperative,intraoperative and 24 hours postoperative period—

Countries

India

Contacts

Public ContactDr Shaila S Kamath

kasturba medical college, mangalore

shaila.kamath@manipal.edu9844090231

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026