Effect of Oral Premedication In Achieving Anesthesia In Hypomineralized Molars affected with symptomatic irreversible pulpitis

Assessment of the effect of oral premedication and two percent lignocaine in achieving anesthesia in children aged 8 to 16 years having hypomineralized molars affected with symptomatic irreversible pulpitis a randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/074126

Enrollment

Registered

2024-09-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K004- Disturbances in tooth formation

Interventions

Intervention1: Ibuprofen 400mg - Oral Premedication: Oral premedication with Tab Ibuprofen 400mg one hour before injecting 2% lignocaine 1:100000 for inferior alveolar nerve block /buccal infiltration

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Children aged between 8 to 15 years and falling under class 1 as per the ASA Classification system. 2. Mandibular 1st and 2nd molar with symptoms of symptomatic irreversible pulpitis 3. Moderate to severe pain 4. Prolonged response to cold test after removing Endo ice-cold spray stimuli. 5. Roots without periapical radiolucency and any periodontal ligament space alterations were evaluated radiographically. 6. Willing to participate in the present trial

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Patient taking any NSAIDs preoperatively. 2. Patient with known allergy to LA or any of its constituents. 3. The patient is not willing to participate in the present trial.

Design outcomes

Primary

Measure	Time frame
To evaluate and compare the effect of oral premedication with a 400 mg Ibuprofen tablet in addition to an inferior alveolar nerve block in terms of pain during access opening in hypo mineralized molars affected with symptomatic irreversible pulpitis in children aged 8 to 15. Timepoint: 1. To assess and evaluate the onset of pulpal anesthesia using electric pulp testing after 15 minutes of administration of local anesthesia. 2. To compare the pain experienced during the procedure with the baseline pain scores. 3. To compare and evaluate the pain scores at three different time intervals: baseline, during the procedure, and post-operative.	—

Measure

Time frame

To evaluate and compare the effect of oral premedication with a 400 mg Ibuprofen tablet in addition to an inferior alveolar nerve block in terms of pain during access opening in hypo mineralized molars affected with symptomatic irreversible pulpitis in children aged 8 to 15. Timepoint: 1. To assess and evaluate the onset of pulpal anesthesia using electric pulp testing after 15 minutes of administration of local anesthesia. 2. To compare the pain experienced during the procedure with the baseline pain scores. 3. To compare and evaluate the pain scores at three different time intervals: baseline, during the procedure, and post-operative.

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Sanjeev Kumar Singh

SMMH Government Medical College, Saharanpur

san.bajaj88@gmail.com9780554348

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026