To compare between platelet-rich plasma and corticosteroids injections in the treatment of Coccydynia disease

Comparative study of efficacy between platelet-rich plasma vs Corticosteroids injections in the treatment of Coccydynia - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/074105

Enrollment

Registered

2024-09-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M533- Sacrococcygeal disorders, not elsewhere classified

Interventions

Intervention1: Platelet rich plasma injection: A single dose of 2 mL injection of platelet rich plasma will be given at baseline and then the patient will be followed-up to 6 month post-therapy. Cont

Eligibility

Inclusion criteria

Inclusion criteria: 1.Persistent pain around the coccyx area for more than 3 months 2.Age between 18 to 65 years 3.Visual analog scale (VAS) score for pain more than or equal to 4 4.BMI 22.3-36.6

Exclusion criteria

Exclusion criteria: 1.Concomitant pathology in coccyx area- folliculitis, pilonidal sinus 2.Systemic disease- any active tumor or malignancy, any active infections 3.History of previous steroid uses (intravenous, intra-articular, oral steroids in last 12 months.) 4.Previous history of fracture around coccyx / any surgery around coccyx 5.Pregnancy 6.History of anti-coagulant use 7.Known case of bleeding disorders 8.Immune-suppressive drugs 9.Inflammatory arthritis (Rheumatic arthritis)

Design outcomes

Primary

Measure	Time frame
To evaluate efficacy of Platelet-rich plasma in treatment of coccydynia over Corticosteroids.Timepoint: Pre-injection, and 4 week ,8 week, 12 weeks and 6 months	—

Secondary

Measure	Time frame
To evaluate efficacy of Platelet-rich plasma in treatment of coccydynia in conjunction with Corticosteroids. Timepoint: Pre-injection, and 4 week ,8 week, 12 weeks and 6 months;To evaluate the adverse effects of Platelet-rich plasma and corticosteroid during the treatment course of Coccydynia. Timepoint: Pre-injection and 4th,8th,12th weeks and 6 months after procedure;To evaluate the effects of local corticosteroid and PRP injection on health-related quality of life of coccydynia patients. Timepoint: Pre-injection, and 4 week ,8 week, 12 weeks and 6 month	—

Measure

Time frame

To evaluate efficacy of Platelet-rich plasma in treatment of coccydynia in conjunction with Corticosteroids. Timepoint: Pre-injection, and 4 week ,8 week, 12 weeks and 6 months;To evaluate the adverse effects of Platelet-rich plasma and corticosteroid during the treatment course of Coccydynia. Timepoint: Pre-injection and 4th,8th,12th weeks and 6 months after procedure;To evaluate the effects of local corticosteroid and PRP injection on health-related quality of life of coccydynia patients. Timepoint: Pre-injection, and 4 week ,8 week, 12 weeks and 6 month

—

Countries

India

Contacts

Public ContactDr Gurudip Das

Associate professor

ortho_gurudip@aiimsbhubaneswar.edu.in7708130970

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026