Health Condition 1: I509- Heart failure, unspecified
Conditions
Interventions
Intervention1: INTRAVENOUS FCM AND ORAL IRON ADMINISTRATION IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILUE: ONCE THE PATIENTS WITH ADHF IS STABILIZED IN EMERGENCY AND SHIFTED TO MEDICAL WARDS, TH
Sponsors
Government Medical College and Hospital Chandigarh Sector
Eligibility
Inclusion criteria
Inclusion criteria: 1.Hospitalized patients with acute decompensated heart failure irrespective of LVEF. 2.Patients with iron deficiency. 3.Patients able to complete six minute walk test ( 6MWT). 4.Individuals above 18 years of age.
Exclusion criteria
Exclusion criteria: 1.Serum ferritin concentrations above 400 microgram/dl. 2.Hemoglobin concentration less than 9 gram/dl. 3.Known sensitivity to ferric carboxy maltose. 4.Blood transfusions, intravenous iron therapy, or erythropoetin therapy within 3 months prior to enrolment. 5.Myocardial infarction in last 90 days. 6.Complex cyanotic congenital heart diseases. 7.Severe concomitant conditions like chronic kidney disease,renal dialysis, chronic lung disease chronic liver disease. 8.Hemolytic anemia or myelodysplastic order or abnormalities in iron storage such as hemochromatosis. 9.Recognized hematological, malignant or other active neoplasia. 10.Chemotherapy, radiation, or other immunosuppressive medication within three months of enrolment. 11.Pregnant women. 12.Serious medical conditions that the investigators determine make it impossible for participants to complete the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Changes in new york heart association (NYHA) functional class at 3 and 6 months. 2.Change in ejection fraction ( by 2d ECHO ) at 6 months. 3.Change in 6MWT distance at 6 months . 4.Change in QOL as assessed by the Minnesota living with heart failure at 6 months . 5.Emergency revisit due to ADHF. 6.Six months readmission due to ADHF. 7.Six month mortality due to ADHF. 8.Six month mortality due to all cardiovascular causes Timepoint: At baseline , 3 months and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| NoneTimepoint: Not applicable | — |
Countries
India
Contacts
Public ContactVinod kumar
Government Medical College and Hospital Chandigarh Sector32
Outcome results
None listed