A clinical trial to compare the efficacy of two different drugs in peribulbar block in patients undergoing small incision cataract surgery.

Efficacy of peribulbar block with the combination of 2 percent lidocaine and 0.75 percent ropivacaine versus 2 percent lidocaine and 0.5 percent bupivacaine in cataract surgery ; a randomised controlled trial. - nil

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/074075

Enrollment

Registered

2024-09-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H25- Age-related cataract Health Condition 2: H28- Cataract in diseases classified elsewhere Health Condition 3: H26- Other cataract

Interventions

Intervention1: lidocaine with ropivacine and Hyaluronidase: 2 % lidocaine with 0.75% ropivacine and 15 IU/ml of Hyaluronidase will be administered as an anaesthetic agent in the peribulbar block given

Eligibility

Inclusion criteria

Inclusion criteria: 1} patients of ASA 1 and 2 2} patients posted for small incision cataract surgery

Exclusion criteria

Exclusion criteria: 1} patients having local sepsis, glaucoma, coagulation abnormality. 2} patient refusal 3} uncooperative patient

Design outcomes

Primary

Measure	Time frame
To compare efficacy of combination of 2% lidocaine with 0.75% ropivacaine and 2% lidocaine with 0.5% bupivacaine for peribulbar block in patients undergoing cataract surgery with respect to : 1} onset of sensory blockade {in minutes} 2}onset of motor blockade {in minutes} 3} duration of post operative analgesia {in minutes}Timepoint: 1)Post operative pain assessment will be done every half hour for 2 hours and hourly for 6 hours. 2)24 hrs analgesic requirement will be noted	—

Measure

Time frame

To compare efficacy of combination of 2% lidocaine with 0.75% ropivacaine and 2% lidocaine with 0.5% bupivacaine for peribulbar block in patients undergoing cataract surgery with respect to : 1} onset of sensory blockade {in minutes} 2}onset of motor blockade {in minutes} 3} duration of post operative analgesia {in minutes}Timepoint: 1)Post operative pain assessment will be done every half hour for 2 hours and hourly for 6 hours. 2)24 hrs analgesic requirement will be noted

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Secondary

Measure	Time frame
To compare the combination of 2% lidocaine with 0.75% ropivacaine & 2% lidocaine with 0.5% bupivacaine in patients undergoing cataract surgery under peribulbar block with respect to : 1} hemodynamic stability 2} side effects- nausea, vomitingTimepoint: 1} hemodynamic stability - systolic blood pressure diastolic blood pressure mean arterial blood pressure heart rate oxygen saturation electrocardiogram will be observed from the application of peribulbar block till the end of procedure. 2}side effects- nausea, vomiting will be observed from the application of peribulbar block till the end of procedure. Time of block will be taken as 0 min & patient will be observered at 5 min intervals till end of procedure.	—

Measure

Time frame

To compare the combination of 2% lidocaine with 0.75% ropivacaine & 2% lidocaine with 0.5% bupivacaine in patients undergoing cataract surgery under peribulbar block with respect to : 1} hemodynamic stability 2} side effects- nausea, vomitingTimepoint: 1} hemodynamic stability - systolic blood pressure diastolic blood pressure mean arterial blood pressure heart rate oxygen saturation electrocardiogram will be observed from the application of peribulbar block till the end of procedure. 2}side effects- nausea, vomiting will be observed from the application of peribulbar block till the end of procedure. Time of block will be taken as 0 min & patient will be observered at 5 min intervals till end of procedure.

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Countries

India

Contacts

Public ContactPrajakta Mehare

NKP Salve institute of medical sciences

bhargavasumita@yahoo.in7219105329

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026