Comparison of propofol with lidocaine on optic nerve sheath diameter in neurosurgical patients as an assessment of laryngoscopy response

Comparison of Propofol with Lignocaine for attenuation of laryngoscopy and intubation induced response on Optic Nerve Sheath Diameter in neurosurgical patients. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/074074

Enrollment

Registered

2024-09-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C719- Malignant neoplasm of brain, unspecified Health Condition 2: S069- Unspecified intracranial injury

Interventions

Intervention1: measuring optic nerve sheath diameter via ultrasound as an indicator of intracrranial pressure.: Comparison of Propofol with Lignocaine for attenuation of laryngoscopy and intubation in

Eligibility

Inclusion criteria

Inclusion criteria: Asa grade 1 and 2, Elective neurosurgical procedure, MP grade 1 and 2

Exclusion criteria

Exclusion criteria: Laryngoscopy and Endotracheal intubation time more than 30 sec, Anticipated difficult airway, Baseline BP less than 100mmHg, Heart Rate less than 60 per min, Any ophthalmic injury, optic nerve pathology, Allergy to drugs used

Design outcomes

Primary

Measure	Time frame
Optic nerve sheath diameterTimepoint: Baseline, 3min after mask ventilation,at intubation, one min after intubation, 5min after intubation, 15min after intubation	—

Secondary

Measure	Time frame
Heart Rate, mean arterial pressure, SBP, DBPTimepoint: Baseline, 3min after mask ventilation,at intubation, one min after intubation, 5min after intubation, 15min after intubation	—

Countries

India

Contacts

Public ContactDr Itishri

Atal Bihari Vajpayee Institute of Medical Sciences and Dr. RML Hospital

Itianesthesia@gmail.com9212400570

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026