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Assessment of the brains blood supply reserve and its relation to postoperative clinical outcome in patients undergoing brain tumour surgery

Assessment of cerebrovascular reserve and clinical outcomes after elective supratentorial tumour surgeries - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/09/074029
Enrollment
100
Registered
2024-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C719- Malignant neoplasm of brain, unspecified

Interventions

Intervention1: Transcranial Doppler: Calculation of the Breath Holding Index (BHI) Intervention2: Heart Rate Variability: Non invasive measurement of the heart rate variability using the ANSIScope dev

Sponsors

NIMHANS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria incudes al adult males and females aged between 50 and 80 years undergoing elective supratentorial tumour surgery at NIMHANS

Exclusion criteria

Exclusion criteria: 1.absent transtemporal transcranial doppler window 2.patients not co-operating for transcranial doppler examination 3.unable to hold breath for atleast 15 seconds 4.undergoing endoscopic pituitary surgery, awake craniotomy, epilepsy surgery 5.loss to follow up at 3 months 6.absence of written informed consent 7.glasgow coma score less than 15

Design outcomes

Primary

MeasureTime frame
To assess pre-operative cerebrovascular reserve by breath holding index in patients undergoing elective supratentorial tumour surgeries and comparing it with the post-operative neurological deficits. (new onset as well as worsening of pre-existing neurological deficits).Timepoint: 1.Breath holding index at pre-operative period and at 3 months follow up. 2.Neurological examination at pre-operative period, at discharge, and 3 months follow up.—

Secondary

MeasureTime frame
To assess changes in cerebrovascular reserve at 3 months after surgery and its comparison to pre-operative statusTimepoint: 1.Cerebrovascular reserve assessment at pre-operative period, and at 3 months follow-up.;To correlate the post-operative neurological deficits (new onset, as well as worsening of pre-existing neurological deficits) to the preoperative autonomic dysfunctionTimepoint: 1.Neurological examination at pre-operative period, at discharge and at 3 months follow up. 2.Autonomic dysfunction at pre-operative period—

Countries

India

Contacts

Public ContactRamesh VJ

National Institute of Mental Health & Neurosciences

drvjramesh@gmail.com9844432607

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026