Health Condition 1: E039- Hypothyroidism, unspecified
Conditions
Interventions
None listed
Sponsors
Dr Smita Naram
Eligibility
Inclusion criteria
Inclusion criteria: 1. Pre diagnosed hypothyroidism (Diagnosis on the basis of Sr. TSH, T3 and T4 levels) individuals of either sex of age group between 18 - 60 years receiving a stable dose of levothyroxin for past 6 months willing to participate in trial with informed written consent. 2. With controlled co-morbidity (viz. Diabetes Mellitus, Hypertension, BMI
Exclusion criteria
Exclusion criteria: 1. Juvenile groups pregnancy and breast feeding women 2. Systemic diseases like hypertension like malignant hypertension, BP systolic greater than or equal to 100 mm/hg and diastolic greater than or equal to 160 mm/hg, diabetes fasting BSL greater than or equal to 200g/dl and postprandial BSL greater than or equal to 350g/dl, known cases of cardiac complications (angina, Myocardial infarction, CAD, post PTCA etc), known cases of pulmonary diseases (pulmonary tuberculosis, ARDS etc), known cases of hepatic complication (Liver cirrhosis, alcoholic liver diseases, jaundice etc) known cases of renal complications (Chronic kidney disease, hydronephrosis), known cases of cancer patients of ongoing chemo-radiation therapy, known cases status epileptics 3. Patients dependent on steroid (who is taking uninterrupted steroid for more than one year in the dose of 0.3 mg/kg/day or higher doses in short span) addictions of narcotic substances 4. Patients with inability to comprehend and complete study assessments as per instructions. 5. Patients with inability to attend or complete the proposed course of intervention and follow-up schedule
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Normalcy of T3, T4 and TSH with reduction in levothyroxine dose, improvement in quality of life and hypothyroid associated symptomsTimepoint: At 12 weeks: Normalcy of T3, T4 and TSH with reduction in levothyroxine dose At 6-12 weeks: improvement in quality of life At 4 weeks: Improvement in hypothyroid associated symptoms | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in associated symptoms like loss of appetite, weight gain, weakness, constipation, muscle stiffness, puffiness, sleep disturbanceTimepoint: Loss of appetite: 2 to 3 weeks weight loss: 3 to 4 kg after 3 months Decrease weakness: after 3 months decrease Constipation: 1 week reduce Muscle stiffness: after one month reduce puffiness: after 2 months reduce Sleep disturbances: after 3 months | — |
Countries
India
Contacts
Public ContactDr Komal Gawali
Dr D Y Patil College of Ayurved and Research Center Pimpri Pune
Outcome results
None listed