To study effect of Intravenous Magnesium Sulphate administration on Postoperative Analgesia in infraumbilical surgeries under spinal anaesthesia.

Effects of intravenous magnesium suphate administration on postoperative analgesia in infraumbilical surgeries under spinal anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073996

Enrollment

Registered

2024-09-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecified

Interventions

Intervention1: Magnesium Sulphate: In the study group 0.5ml (250mg) of Inj. Magnesium Sulphate IV was given, followed by 500mg (25mg/ml) infusion was given at 20ml/hr for 1hour through intravenous rou

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18-65years, undergoing lower abdominal surgeries BMI 20-35 kg/m2 ASA Grade I and II Mallampati Score Class I and II Patients giving consent to be part of the study Hemodynamically Stable Patients Routine Investigations (CBC, RFT, LFT, SE)- within normal limits Duration of Surgery less than 4 hours

Exclusion criteria

Exclusion criteria: Patients unwilling to Consent Patients with ASA Grade III or IV Hemodynamical Instability (Hypotension, Bradycardia) Severe or Uncontrolled Diabetes or Hypertension, CVD Cardiovasular Disease (CAD, HF, Cardiomyopathies, Valvular Heart Diseases) Hepatic Impairment, Renal Impairment Known case of Coagulopathies, abnormal hemoglobin, Anaemia Known case of Kyphoscoliosis and deformity of spine

Design outcomes

Primary

Measure	Time frame
To study effect of Intravenous Magnesium Sulphate administration on postoperative ananlgesia in infraumbilical surgeries under spinal anaesthesiaTimepoint: After administration of the spinal anaesthesia, comparison between the two groups of onset and duration of sensory and motor blockade, duration of analgesia and time of rescue of analgesia will be assessed at baseline, after injection of study drug at immediate postop, 15mins, 30mins, 45mins, 60minms, 4hrs, 8hrs, 12hrs, 16hrs, 20hrs, 24hrs and assessment VAS score	—

Measure

Time frame

To study effect of Intravenous Magnesium Sulphate administration on postoperative ananlgesia in infraumbilical surgeries under spinal anaesthesiaTimepoint: After administration of the spinal anaesthesia, comparison between the two groups of onset and duration of sensory and motor blockade, duration of analgesia and time of rescue of analgesia will be assessed at baseline, after injection of study drug at immediate postop, 15mins, 30mins, 45mins, 60minms, 4hrs, 8hrs, 12hrs, 16hrs, 20hrs, 24hrs and assessment VAS score

—

Secondary

Measure	Time frame
To study effect of Intravenous Magnesium Sulphate administration on postoperative ananlgesia in infraumbilical surgeries under spinal anaesthesiaTimepoint: Duration of analgesia will be assessed post surgery after administration of magnesium sulphate & time of rescue analgesia will be assessed	—

Countries

India

Contacts

Public ContactDr Shahbaz Hasnain

DR D.Y. PATIL MEDICAL COLLEGE, HOSPITAL AND RESEARCH CENTRE, PIMPRI, PUNE

shahbazhsnn@gmail.com9764621253

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026