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Nebulised dexmedetomidine efficacy in reducing haemodynamic response to laryngoscopy and intubation.

Evaluation of efficacy of nebulised dexmedetomidine in attenuation of haemodynamic response to laryngoscopy and intubation. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073995
Enrollment
160
Registered
2024-09-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulised dexmedetomidine will be given and attenuation of haemodynamic response to laryngoscopy and intubation will be recorded.: Nebulised Dexmedetomidine will be given at a dosage o

Sponsors

Dr Tarandeep Singh Bajwa
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: o American Society of Anaesthesiologists class 1 and 2 patients. o Mallampati Grading I and II. o Undergoing elective surgery under general anaesthesia and endotracheal intubation needed. o Patient between age 18 to 60 years.

Exclusion criteria

Exclusion criteria: o American Society of Anaesthesiologists class III and IV. o Patient not consenting for the study. o Predicted difficulty airway. o Known allergy to dexmedetomidine o Patient on B-blockers o Pregnant females. o Kidney failure o Uncontrolled hypertensive patient o Seizure disorders. o Patient taking medications such as anti-depressants or anti-psychotics. o Patients with decrease cardiac output. o Obese patient with Body mass index of more than 30 kg/metre square. .

Design outcomes

Primary

MeasureTime frame
Study is to evaluate the two groups in order to assess the following VITALS: heart rate, systolic and diastolic blood pressure, mean arterial pressure.Timepoint: Heart rate , the blood pressure (systolic , diastolic and the mean arterial pressure will be noted by the baseline vitals, the post-nebulization (post-neb), and the post-intubation at 1, 5, and 10 minutes will be noted.

Secondary

MeasureTime frame
To study any adverse effect of drug such as bradycardia,, hypotension, coughing and sore throat.Timepoint: In postoperative ward after extubation.

Countries

India

Contacts

Public ContactDr Tarandeep Singh Bajwa

Maharishi Markandeshwar Medical college and Hospital

sachinkg78@gmail.com9877484849

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026