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Clinical profile of patients presenting with ascending weakness of both lower limbs followed by upper limbs. A detailed study on Gullian Barre Syndrome

Clinical Profile of Gullian Barre Syndrome in a rural hospital in Central India - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/09/073973
Enrollment
45
Registered
2024-09-17
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G379- Demyelinating disease of central nervous system, unspecified

Interventions

Intervention1: nil: nil

Sponsors

DR Mathakala Aparna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Confirmed Diagnosis: Patients with a confirmed diagnosis of GBS based on clinical criteria, electrophysiological studies, and cerebrospinal fluid analysis. 2. Age Range: Include patients of age above 18 years 3. Patients presenting with Acute flaccid Paralysis with 28 days of illness. 4. Consent: Patients or their guardians must provide informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with features of Hypokalemic periodic paralysis. 2. Patients with features of upper motor neuron signs and symptoms. 3. Patients admitted with history of exposure to toxins. 4. Patients with severe terminal illness. 5. Patients in whom the weakness progressed for more than 4 weeks. 6. Patients age less than 18 years of age 7.Patients with a chronic form of GBS, such as chronic inflammatory demyelinating polyneuropathy (CIDP), to maintain focus on the acute presentation.

Design outcomes

Primary

MeasureTime frame
Prognosis of the disease will be studied based on the power improvement in all limbs.Timepoint: at every 2 weeks for 6 months power will be assessed.

Secondary

MeasureTime frame
ICU requirement of the patient will be assessed for how many days.Timepoint: at 2 weeks, 4 weeks, 6 weeks. for every 2 weeks assesemenet will be done

Countries

India

Contacts

Public ContactDR Mathakala Aparna

Jawaharlal Nehru Medical College

harshjan80@gmail.com9764031941

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026