Health Condition 1: S061- Traumatic cerebral edema
Conditions
Interventions
Intervention1: Ketamine 1-2 mg/kg IV: Patients with traumatic brain injury who fit ininclusion criteria will receive Ketamine 1-2 mg/kg IV for RSI. USG guided Optic Nerve Sheath Diameter will be measu
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: With traumatic brain injury presenting to ED and requiring a rapid sequence intubation. Patient relatives are willing to participate in the study
Exclusion criteria
Exclusion criteria: Hemodynamic instability( hyper or hypotension) during RSI Predicted difficult intubation by LEMON scoring Patients with open skull injuries Patients with eyeball globe injuries, orbital mass or tumors. Patients with H/O any neurosurgical procedures. Nontraumatic brain injuries pregnancy Anti-edema therapy like Mannitol infusion started before arrival at ED Contraindication or Hypersensitivity to any used drug. • Other organ injury causing likelihood of low GCS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average change in optic nerve sheath diameter before and after administration of induction drugsTimepoint: Parameters Wii be taken 3 minutes before induction ,5 and 10 minutes following induction.The patient will be followed up for next 24 hour. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Hemodynamic changes 2. Successful first pass intubation rates 3.To check the duration of sedative efficacy among the two groups.Timepoint: Measurements are taken just before induction and 5 minutes, 10 minutes following induction. | — |
Countries
India
Contacts
Public ContactDr Subhasree Das
AIIMS,Bhubaneswar
Outcome results
None listed