Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: 50 mcg Dexmedetomidine in 5 ml of NormalSaline: Nebulization of the patient with 50 mcg Dexmedetomidine in 5 ml of Normal saline for 10 minutes with oxygen at 10 L/min before 30 minutes
Sponsors
Rajendra institute of medical sciences Ranchi
Eligibility
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologist (ASA) physical grade 1 and 2 2. Elective surgery of duration 2-3 hours under general anesthesia
Exclusion criteria
Exclusion criteria: 1. Patients with previous sore throat or recent upper respiratory tract infection 2. Using steroids or analgesia in the last 48 hours 3. Patients of asthma or chronic obstructive pulmonary disease, neuromascular diseases, mental disease 4. Heavy smokers 5. Allergic to the drugs used in this study 6. Mallampati grade more than 2 7. Obese patients with body mass index more than 35 kg per meter square, pregnant women 8. Intubation time more than 60 seconds and traumatic intubation 4.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To record the incidence and severity of sore throat after surgeryTimepoint: 0 hour post- surgery 2 hours post- surgery 4 hours post- surgery 6 hours post- surgery 24 hours post- surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To record the hemodynamics- Mean arterial blood pressure, Heart rate 2. To record any related side effectsTimepoint: At baseline After nebulization After laryngoscopy 15 minutes after nebulization 30 minutes after nebulization 45 minutes after nebulization 60 minutes after nebulization 75 minutes after nebulization 90 minutes after nebulization 105 minutes after nebulization 0 hour post- surgery 2 hours post- surgery 4 hours post- surgery 6 hours post- surgery 24 hours post- surgery | — |
Countries
India
Contacts
Public ContactDr Dipali Singh
Rajendra institute of medical sciences,Ranchi
Outcome results
None listed