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Effect of children undergoing Wilms tumour surgery

Effectiveness of prophylactic tranexamic acid for reducing blood loss in children undergoing wilms tumour surgery: a randomized control study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073921
Enrollment
60
Registered
2024-09-13
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N182- Chronic kidney disease, stage 2 (mild)

Interventions

Intervention1: TXA will be given in a loading dose of 50 mg/kg followed by an infusion of 5 mg/kg/h during surgery in interventional arm of study.: TXA will be given in a loading dose of 50 mg/kg foll

Sponsors

Operation Theater
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age less than 10 year Planned elective Wilms tumour surgery Both with or without chemoradiotherapy

Exclusion criteria

Exclusion criteria: Refusal of patient’s attendant Age more than 10 years Presence of haematological, coagulation, hepatic, renal, or vascular disorders Platelet count less than 1.5 lakh/ml INR value more than 1.5 Ingestion of nonsteroidal anti-inflammatory agents within 14 days Allergy to study drugs

Design outcomes

Primary

MeasureTime frame
Blood loss quantity in each groupTimepoint: Blood loss quantity in each group—

Secondary

MeasureTime frame
Blood transfusion quantity required in each group Postoperative Hb level after surgery Intraoperative haemodynamic parameters- Heart rate and SBP Need of vasopressor infusion Surgical field quality Any adverse event Timepoint: 2hrs to 48hrs—

Countries

India

Contacts

Public ContactDr Sateesh Verma

King Georges Medical University Lucknow

sateeshverma24@gmail.com7379837390

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026