Health Condition 1: O432- Morbidly adherent placenta
Conditions
Interventions
Intervention1: FIBRINOGEN: All participants in the intervention group shall receive single dose of fibrinogen 2 g i.v. in 100 ml saline (taped with opaque covering), as soon as the neonate is delivere
Sponsors
All India Institute Of Medical Sciences New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1.) Age > 18 years 2.) Established diagnosis of PAS 3.) Caesarean section planned under general anaesthesia 4.) Informed written consent
Exclusion criteria
Exclusion criteria: 1.) Unwillingness to provide consent, 2.) Known case of coagulation disorders, 3.) Patient on anticoagulants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.) Estimated blood loss intraoperatively and within 24 hours of surgery 2.) Volume of blood transfusion intraoperatively and within 24 hours of surgery.Timepoint: 1.) Estimated blood loss intraoperatively and within 24 hours of surgery 2.) Volume of blood transfusion intraoperatively and within 24 hours of surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.) Incidence of thromboembolic complications, if any within 7 days. 2.) Need of blood product transfusions at 24 hours and 7 days of drug administration 3.) Incidence of severe PPH, mortality. 4.) Incidence of allergic reactions 5.) ROTEM and its correlation with laboratory parameters and clinical outcomes. Timepoint: 1) 24 hours after surgery 2) Seven days after surgery | — |
Countries
India
Contacts
Public ContactAmit Kumar Malviya
All India Institute Of Medical Sciences, New Delhi
Outcome results
None listed