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Comparison of reduction of pain on propofol injection with lignocaine admixture and pretreatment

Comparison of lignocaine pretreatment with torniquet and lignocaine admixture with propofol in alleviating pain on propofol injection - A randomised clinical trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073843
Enrollment
260
Registered
2024-09-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Lignocaine: pretreatment with 1% lignocaine with torniquet is used followed by propofol Control Intervention1: Lignocaine admixture: Mixing lignocaine to propofol before administration

Sponsors

Jawaharlal Institute of Postgraduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18-60 years ASA class I, II Patients undergoing elective surgery under general anaesthesia in whom induction with propofol is planned.

Exclusion criteria

Exclusion criteria: patients with known allergies to Propofol or any of its components patients planned for rapid sequence induction, pregnant patients. patients with difficult venous access or thin caliber veins. Patients on any analgesic medications pre operatively

Design outcomes

Primary

MeasureTime frame
To compare the incidence of pain during propofol injection between pretreatment with lignocaine with tourniquet and lignocaine admixture in alleviating pain on propofol injection using VRS score.Timepoint: after 15s of propofol injection or as soon as patient complains of pain—

Secondary

MeasureTime frame
To compare the Severity of pain on propofol injection between the groups using VRSTimepoint: after 15s of propofol injection or as soon as patient complains of pain—

Countries

India

Contacts

Public ContactDr Fathima Amna P

Jawaharlal Institute of Postgraduate Medical Education and Research , Puducherry

drmohanvk@gmail.com9841546265

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026