A study to compare the effectiveness of thioglycolic acid peel alone vs thioglycolic acid peel and oral pentoxifylline in pigmented purpuric dermatosis.

Comparative study between ten percent thioglycolic acid peel and ten percent thioglycolic acid peel plus oral pentoxifylline in pigmented purpuric dermatosis-A randomised control study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073819

Enrollment

Registered

2024-09-12

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L817- Pigmented purpuric dermatosis

Interventions

Intervention1: Thioglycolic acid peel and tablet pentoxifylline: 10% Thioglycolic acid peel once weekly plus tablet pentoxifylline 400mg once daily for 6 weeks Control Intervention1: thioglycolic acid

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with ppd over legs.

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating female. 2.Patients who did not give consent for study. 3.patients who are on anticoagulants. 4.Patients having hypersensitivity to thioglycolic acid. 5.patients having varicosities, local inflammation or infection. 6.Patients with history of pulmonary disease or acute respiratory disease. 7.Patients exhibiting intolerance to pentoxifylline, xanthines. 8.Patients with recent cerebral and/or retinal hemorrhage. 9.Patients with acute myocardial infarction or severe coronary artery disease. 10.Patients with peptic ulcers.

Design outcomes

Primary

Measure	Time frame
skin hyperpigmentation indexTimepoint: 0,3rd,6th week	—

Secondary

Measure	Time frame
Analysis by independent dermatologistTimepoint: 0,3rd,6th week	—

Countries

India

Contacts

Public ContactDr Rasmi ranjan pradhan

S.C.B. medical college and hospital

titoon@rediffmail.com7381231102

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026