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Comparison of dexmedetomidine, ketamine & magnesium sulphate nebulisation in preventing post operative sore throat

A Comparative Study Of Preoperative Dexmedetomidine , Ketamine & Magnesium Sulphate Nebulisation For Incidence Of Postoperative Sore Throat After Endotracheal Intubation. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073816
Enrollment
150
Registered
2024-09-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Nebulisation: Ketamine 50mg (1ml) with 4ml saline Dexmedetomidine 50 micrograms 4ml saline Magnesium sulphate 2ml 50% w/v ( for time duration of 15 minutes) Control Intervention1: KETAM

Sponsors

Department of Anaesthesiology and Critical Care
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All subjects scheduled for elective operations requiring general anaesthesia and tracheal intubation . ASA grade I , II . Mallampatti grading I , II

Exclusion criteria

Exclusion criteria: Patients with history of sore throat Mallampati grading III , IV H/O Drug Allergy

Design outcomes

Primary

MeasureTime frame
The primary aim is to investigate the impact of nebulisation with ketamine , magnesium sulphate and dexmedetomidine on incidence of postoperative sore throat following endotracheal intubationTimepoint: To evaluate sore throat in patients after extubation at 0 hours,2 hour,4 hours,8 hours ,12 hours , 24 hours—

Secondary

MeasureTime frame
To assess the severity of post operative sore throat in patients treated with each of these nebulization agents.Timepoint: To evaluate sore throat in patients after extubation at 0 hours,2 hours, 4hours , 8 hours, 12 hours ,24 hours—

Countries

India

Contacts

Public ContactDR MUSKAN

N.C. MEDICAL COLLEGE & HOSPITAL , ISRANA , PANIPAT

muskanpanwar1501@gmail.com8222814101

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 9, 2026