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Role of curcumin in improving vision in advanced glaucoma patients

Efficacy of oral curcumin in improving visual function in eyes with advanced stage glaucoma - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073759
Enrollment
50
Registered
2024-09-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H42- Glaucoma in diseases classified elsewhere

Interventions

Intervention1: Oral curcumin capsule: One (1) capsule of curcumin will be given orally /per day for three (3) months, Curcumin acts as an anti-oxidative and anti-inflammatory agent. Control Interventi

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The following patients will be included in the study 1.Patients willing to give consent for the study 2.Age 18 to 80 years. 3.Patients with advanced stage glaucoma in at least one eye and well-controlled IOP (less than 16 mmHg) in that eye with a Snellen visual acuity of at least 6 by 36. 4.If both eyes of the patient were eligible the eye with the better visual field was included in the study

Exclusion criteria

Exclusion criteria: 1.Not willing to follow up. 2.Age less than 18 years 3.Any patient with recent ocular surgery in past 3 months or secondary inflammatory conditions causing glaucoma eg, vernal keratoconjunctivitis (VKC), uveitix, sclerouveitis etc. 4.Patients with contraindications to curcumin or any related allergies. 5.Patients with any other disease that might have contributed to visual field loss at the time of initial visual-field test such as other optic neuropathies, stroke, brain tumors, retinal vein or artery occlusion, macular disease, cataract and proliferative diabetic retinopathy. 6.Any recent surgery in last 3 months

Design outcomes

Primary

MeasureTime frame
1.Perimetry 2.Cup-Disc-Ratio (CDR) 3.Optical Coherence Tomography Angiography (OCTA) Timepoint: 4 Weeks, 6 Weeks, 12 Weeks

Secondary

MeasureTime frame
Multifocal Electroretinography (Mf-erg)Timepoint: 4 Weeks, 6 Weeks, 12 Weeks

Countries

India

Contacts

Public ContactShikha Gupta

Aiims, New Delhi

shikhagupta@aiims.edu01126593171

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026