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Impact of added LASER treatment on levels of Monocyte Chemoattractant Protein-1 in gingival crevicular fluid during non-surgical periodontitis management - a randomized clinical trial with split-mouth design

Effects of Adjunctive LASER therapy on GCF Monocyte Chemoattractant Protein-1 levels in Non-Surgical Management of Periodontitis-A Split Mouth Randomized clinical trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073737
Enrollment
21
Registered
2024-09-10
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Scaling and root planing: scaling and root planing is the gold standard procedure.It is the deep cleaning of the root surface of the teeth Control Intervention1: Laser: subgingival cure

Sponsors

DrHarini guna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patient exhibited good general health with no evidence of underlying systemic disease and with presence of atleast 20teeth

Exclusion criteria

Exclusion criteria: Patient who were smokers,who had underwent Phase 1 therapy in last 3 months, consumes antibiotics in last 1month,history of allergy,diabetes,hypertension,coronary artery disease,any invasive cardiac treatment within last 6months or any inflammatory disease such as idiopathic pulmonary fibrosis,osteoarthritis,rheumatoid arthritis,renal disease or tumors,pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
To evaluate the MCP-1 level in GCF in periodontitis patient.Timepoint: 1 month

Secondary

MeasureTime frame
: To evaluate the periodontal status using plaque index, gingival index, probing depth, clinical attachment level.Timepoint: at 6 weeks

Countries

India

Contacts

Public Contactharini guna

SRI VENKATESHWARAA DENTAL COLLEGE

gharini12042000@gmail.com6369840002

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026