Difference in artificial bone material and naturally obtained bone material in terms of new bone formation following removal of infection

Comparative Evaluation of the Efficacy of Eggshell Derived Hydroxyapatite (EHA) with Commercial Available Synthetic Hydroxyapatite (SHA) In Bone Regeneration following Periapical Cyst Enucleation. - nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073715

Enrollment

Registered

2024-09-10

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Egg shell derived hydroxyapatite bone graft: To evaluate the efficacy of Egg shell derived hydroxyapatite bone graft in bone regeneration following periodical cyst enucleation at 3,6,9

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with periapical cystic lesions (1.5-2 cm in diameter) of the maxilla and mandible involving up to three teeth, as confirmed by clinical and radiological evaluations, will be included in the study. 2. Patients in the age group of 18-40 years. 3. Patients who will give written informed consents.

Exclusion criteria

Exclusion criteria: 1. Immunocompromised individuals including those with severe debilitating diseases, 2. Pregnant and lactating female participants. 3. Individuals with endocrine disorders. 4. Patients in which satisfactory endodontic treatment cannot be done.

Design outcomes

Primary

Measure	Time frame
The effect of grafting will be evaluated using digital radiographic imaging technique and computer densitometry in bone regeneration at time intervals of 3,6 and 9 months following periapical cyst enucleation.Timepoint: The effect of grafting will be evaluated using digital radiographic imaging technique and computer densitometry in bone regeneration at time intervals of 3,6 and 9 months following periapical cyst enucleation.	—

Measure

Time frame

The effect of grafting will be evaluated using digital radiographic imaging technique and computer densitometry in bone regeneration at time intervals of 3,6 and 9 months following periapical cyst enucleation.Timepoint: The effect of grafting will be evaluated using digital radiographic imaging technique and computer densitometry in bone regeneration at time intervals of 3,6 and 9 months following periapical cyst enucleation.

—

Secondary

Measure	Time frame
The effect of grafting will be evaluated using digital radiographic imaging technique and computer densitometry in bone regeneration at time intervals of 3,6 and 9 months following periapical cyst enucleation.Timepoint: 4,7,10 months	—

Countries

India

Contacts

Public ContactDrBMRudagi

Dr.DY Patil dental college and hospital,Dr.DYPatil vidyapeeth,Pune

drbmr17@gmail.com9673494111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026