Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Targeted Axillary Dissection: Targeted Axillary dissection guided by pre-NACT axillary node clipping and peri-operative radiological guidance
Control Intervention1: None: None
Control I
Sponsors
All India Institute of Medical Sciences Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: • Patients with cT1-3 N1 M0 carcinoma breast irrespective of histology or hormonal receptor status scheduled to receive neoadjuvant chemotherapy (NACT) • Patients with FNAC or biopsy proven positive axillary lymph node
Exclusion criteria
Exclusion criteria: • Patients with previous ipsilateral axillary surgery • Patients with previous radiotherapy to ipsilateral axilla • Patients allergic to methylene blue dye or fluorescein dye • Patients who have palpable axillary lymph nodes on clinical examination post-NACT
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the identification rate of TAD with ultrasound guidance in post-NACT carcinoma breast patientsTimepoint: Intra-operative | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine False Negative rate (FNR) of TAD with ultrasound guidance in post-NACT carcinoma breast patientsTimepoint: Perioperative;To determine Technical Failure Rate (TFR) of clipped node biopsy – percentage of patient in which clipped node could not be identified and removed.Timepoint: Intra-operative;To the evaluate the concordance between clipped lymph node (CLN) and sentinel lymph node (SLN)Timepoint: Intra-operative | — |
Countries
India
Contacts
Public ContactNivedita Sharma
AIIMS, Jodhpur
Outcome results
None listed