Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1. Treatment Na?ve patients with oral cavity squamous cell carcinoma 2. Requiring anterior mandibular resection with midline mandibular defect (resection including both canines or one/both angles of mandible) 3. Age more than 18 years 4. Willing to give the consent 5. Conversant with Hindi, Marathi,or English
Exclusion criteria
Exclusion criteria: 1.Any significant comorbidity affecting the procedure being done under general anesthesia at the discretion of the operating surgeon. 2.Reconstruction done with other flaps such as Pectoralis Major Myocutaneous Flap/Thoracodorsal Artery Perforator Flap.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome is quality of life at 6 months by measuring mean (SD) composite physical function score of UW-QOL toolTimepoint: Baseline: Patients will complete UW-QOL v4 and EQ-5D-5L questionnaires, along with a swallowing assessment. 4-8 weeks post-surgery: Patients will again complete the UW-QOL v4, EQ-5D-5L, and undergo a swallowing assessment. 6 months post-surgery: The same questionnaires and swallowing assessment will be administered. 12 months post-surgery: Final follow-up with UW-QOL v4, EQ-5D-5L, and swallowing assessment will be done | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome is to assess the quality of life in terms of duration of tracheostomy tube and feeding tube retained at 6 monthsTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Shivakumar Thiagarajan
Tata Memorial Hospital, Parel, Mumbai
Outcome results
None listed