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Comparison Intravenous Beta blocker and lignocaine for control of heart rate and blood pressure during tracheal intubation

To Compare the efficacy of esmolol 0.5 mg/kg versus lidocaine 1.5 mg/kg to attenuate the hemodynamic stress response to larynoscopy and endotracheal intubation - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073643
Enrollment
72
Registered
2024-09-09
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: K353- Acute appendicitis with localizedperitonitis Health Condition 3: K802- Calculus of gallbladder without cholecystitis Health Condition 4: N202- Calculus of kidney with calculus of ureter Health Condition 5: H661- Chronic tubotympanic suppurative otitis media

Interventions

Intervention1: Use of Injection Esmolol for Attenuation of larynogoscopy.: Single Injection of Esmolol 0.5mg/kg intravenously 90 second over 30 seconds before Tracheal intubation Control Intervention

Sponsors

PACIFIC MEDICAL COLLEGE AND HOSPITAL UDAIPUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient Belonging to ASAI and II Patient weighing 40 to 60 kg Patient Plan for General Anaesthesia

Exclusion criteria

Exclusion criteria: Patients for Emergency Surgeries. Refusal by Patients. ASAIII and above

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of Esmolol 0.5mg/kg versus Lidocaine 1.5mg/kg to attenuate the hemodynamic stress response during laryngoscopy and endotracheal intubationTimepoint: To compare the efficacy of Esmolol 0.5mg/kg versus Lidocaine 1.5mg/kg to attenuate the hemodynamic stress response during laryngoscopy and endotracheal intubation at baseline,before induction and 1,3,5,7 and10 minutes after induction—

Secondary

MeasureTime frame
To compare the degree of hypotension with both the drugs. To compare side effects of both the drugs. Timepoint: Perioperative period—

Countries

India

Contacts

Public ContactDr Vikram Singh Rathore

Uttar Pradesh University Of Medical Sciences

vikram2012.mmc@gmail.com8826719977

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026