Health Condition 1: D259- Leiomyoma of uterus, unspecified Health Condition 2: D259- Leiomyoma of uterus, unspecified
Conditions
Interventions
Intervention1: Intrathecal Clonidine with Bupivacaine: In patients undergoing open myomectomy we will give intrathecal clonidine with bupivacaine before starting surgery to provide anaesthesia. In thi
Sponsors
Jawaharlalal Institute of Postgraduate Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Patient age between 18-50 years ASA physical status 1 and 2 Patients requiring intra myometrial Vasopressin injection
Exclusion criteria
Exclusion criteria: H/O allergy to study drugs (Local anesthetics, Vasopressin and Clonidine). Pre-existing arrythmia, Heart block and structural heart disease. Any contraindications for spinal anesthesia. Short stature (Height BMI > 30kg/m2 Pregnant and lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare hypertensive response (defined as mean arterial pressure more than or equal to 10 mm of Hg from the baseline value within 60 minutes of intramyometrial vasopressin injection between study and control group.Timepoint: Every minute for first 20 minutes after intramyometrial vasopressin injection , every 5 minutes there after till 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare systolic and diastolic blood pressure between groups To compare heart rate between groups To compare side effects like sedation, dry mouth, bradycardia or tachycardia episodes Postoperative motor and sensory regression time First dose analgesia requirement timeTimepoint: upto 24 hours following surgery | — |
Countries
India
Contacts
Public ContactDr Sakthirajan P
Jawaharlal Institute of Postgraduate Medical Education and Research
Outcome results
None listed