Health Condition 1: B95-B97- Bacterial and viral infectious agents
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: nil: nil
Sponsors
Dr Dhruva Chaudhry
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age above 18years. 2. Diagnosis of sepsis with predefined criteria. 3. Admitted in ICU/ high dependency unit (HDU).
Exclusion criteria
Exclusion criteria: 1. Acute Exacerbation COPD. 2. Any chronic respiratory illness with pCO 2 more than 50mm Hg. 3. Liver dysfunction defined as encephalopathy and impaired synthetic function (international normalized ratio [INR] of =1.5) 22 , a patient with cirrhosis or pre-existing liver disease. 4. Pregnant female. 5. End stage malignancy cases or cases admitted with treatment related complications. 6. Do not resuscitate orders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Role of Central venous to arterial carbon dioxide gradient in predicting sepsis outcomesTimepoint: Time at which patient gets discharged from the ICU or died in the ICU | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in ?pCO 2 & association with lactate clearance. Timepoint: Time at which patient gets discharged from the ICU or died in the ICU;Change in ?pCO 2 from 0 to 6 hours & association with sepsis outcomes. Timepoint: Time at which patient gets discharged from the ICU or died in the ICU;Change in ?pCO2 from 0 to 2 hours & association with sepsis outcomes.Timepoint: Time at which patient gets discharged from the ICU or died in the ICU | — |
Countries
India
Contacts
Public ContactSamruddhi Chougale
Pandit B.D Sharma, PGIMS, Rohtak
Outcome results
None listed