Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 2: K769- Liver disease, unspecified
Conditions
Interventions
Intervention1: Portal vein embolization using NBCA glue plus vascular plug: Portal vein embolization using NBCA glue and Amplatzer nitinol vascular plug. Both of these are permanent embolic material.
Sponsors
Dr Suman Mandal
Eligibility
Inclusion criteria
Inclusion criteria: All patients with inadequate FLR planned for portal vein embolization before major liver resections.
Exclusion criteria
Exclusion criteria: 1. Patients denying consent 2. Locally unresectable disease 3. Distant metastasis 4. Child Pugh B and C cirrhotic patients 5. Clinically significant portal hypertension 6. Extensive intrahepatic portosystemic shunts 7. Tumor thrombus extending into portal vein 8. Women during pregnancy or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of absolute FLR hypertrophy at 14 days and 28 days after PVE. FLR absolute hypertrophy was calculated as (FLR volume after PVE-FLR volume before PVE) x 100/ (FLR volume before PVE)Timepoint: At 14 and 28 days post portal vein embolization | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of additional volumetric liver growth variables (degree of hypertrophy and kinetic growth rate) between the PVE groups includedTimepoint: At 14 and 28 days post portal vein embolization;Total contrast material volume usedTimepoint: At the time of portal vein embolization procedure;Pain intensity according to visual analog scale (range, 0â??10)Timepoint: At the time of portal vein embolization procedure;total fluoroscopy and procedure timeTimepoint: At the time of portal vein embolization procedure;Minor and major complications, and hospital stayTimepoint: During hospital stay post procedure | — |
Countries
India
Contacts
Public ContactDr Tara Prasad Tripathy
AIIMS Bhubaneswar
Outcome results
None listed