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Use of a hormone to reduce giving blood traansfusion in less than 1 kg newborns

Use of Erythropoetin in reducing blood tranfusion in Extremely Low Birth Weight neonates: A Prospective Observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/09/073586
Enrollment
64
Registered
2024-09-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P070- Extremely low birth weight newborn

Interventions

Intervention1: Inj Erythropoietin: Inj erythropoietin is started at birth at 400 IU/kg/dose thrice a week up to 35 weeks of postmenstrual age.

Sponsors

Seth GS Medical College and KEM Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Preterm infants less than 28 weeks of gestation and/or & birth weight less than 1000 gms

Exclusion criteria

Exclusion criteria: Any known hematological disorders and hemoglobinopathies Hydrops fetalis Critical Congenital Heart Disease Life threatening gross congenital anomalies Any intrauterine transfusion

Design outcomes

Primary

MeasureTime frame
need for more than 1 blood transfusion in extremely low birth weight infants.Timepoint: 60days

Secondary

MeasureTime frame
Bronchopulmonary dysplasiaTimepoint: 60 days;Intraventricular haemorrhage all gradesTimepoint: 28 days;Length of hospital stayTimepoint: 60 days;Mortality during initial hospital stay (all causes).Timepoint: 28 days;Necrotizing enterocolitisTimepoint: 28 days;Number of Blood transfusion per infant.Timepoint: 60 days;Periventricular leukomalaciaTimepoint: 60 days;Proven sepsis (clinical symptoms and signs of sepsis and positive blood culture for bacteria or fungi).Timepoint: 60 days;Retinopathy of prematurity (ROP) (any stage and stage 3 or more) Timepoint: 60 days;The total volume (mL/kg or mL/kg/day) of RBCs transfused per infant.Timepoint: 60 days

Countries

India

Contacts

Public ContactAnitha Ananthan

Seth GS Medical College and KEM Hospital

amruta.amte.aa@gmail.com09769660870

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026