Does 5-flurouracil overweight the modified Carnoy’s solution for chemical cauterisation after peripheral ostectomy in patients with odontogenic keratocyst ?: a comparative study

Comparative Evaluation of Post-Operative outcomes of Modified Carnoy’s Solution Versus 5-Flurouracial Used For Chemical Cauterization Following Enucleation And Peripheral Ostectomy In Patients With Odontogenickerato Cyst - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073579

Enrollment

Registered

2024-09-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K099- Cyst of oral region, unspecified

Interventions

Intervention1: 5FU: GROUP II – TRETMENT WITH 5-FU After peripheral ostectomy sterile ribbon gauze will be coated with 5-FU (500 mg ampule) 10 ml and packed into the surgical cavity. Wound will be clos

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients included in this study will be histologically proven cases of OKC with the age range of 18 - 70 years. 2. Patients having cystic lesion of size more than 2 cm in greatest diameter. 3. Patient having interincisal mouth opening of at least 30mm. 4. Patients who are non-smokers and non-alcoholic.

Exclusion criteria

Exclusion criteria: 1. Patients having cystic lesion of size less than 2 cm in diameter. 2. All patients who are contraindicated with multiple cystic lesion 3. All previously treated patient with same diagnosis of OKC. 4. Patients with immunocompromised status. 5. Pregnant and Lactating females.

Design outcomes

Primary

Measure	Time frame
Assess the rate of Odontogenic keratocyst recurrence within a defined follow-up period. 5-Fluorouracil (5-FU): Compare the recurrence rate with that of Modified Carnoy’s Solution. Timepoint: 6 month ,12 month and 18 month	—

Secondary

Measure	Time frame
NILLTimepoint: NA	—

Countries

India

Contacts

Public ContactDr. Nidhi Bodiwala

nidhi19697bodiwala@gmail.com07741013662

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026