Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Antimicrobial photodynamic therapy: non surgical periodotnal therapy + A diode laser used along with a photosensitizer/dye for 3 months .
Intervention2: conventional regenerative therap
Sponsors
Rameshwari Singhal
Eligibility
Inclusion criteria
Inclusion criteria: Adults between 18 to 50 years of age Bilateral defects with probing depth greater than 5mm and clinical attachment level greater then equal to 6mm associated with an intrabony defect greater than equal to 3mm Full mouth plaque scores and full mouth bleeding scores 20 percent after non surgical periodontal therapy Nonsmokers or former smokers who have not smoked within 6 months of study initiation Vital or root canal treated tooth with no associated endodontic pathology
Exclusion criteria
Exclusion criteria: Patients with clinically significant or unstable systemic diseases or compromised healing potential Patients with history of antibiotic nonsteroidal antiinflammatory medication or on drug affecting periodontal status for greater than equal to 2weeks prior to enrolment in the study Pregnant or lactating women History of periodontal surgery within last one year of enrolment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in pocket probing depth clinical attachment loss and MMP1 levels healing dynamicsTimepoint: Reduction in pocket probing depth clinical attachment loss and MMP1 levels healing dynamics at baseline and 21days 3months and 6months | — |
Secondary
| Measure | Time frame |
|---|---|
| patient perceived satisfactionTimepoint: 6months | — |
Countries
India
Contacts
Public ContactRameshwari Singhal
King Georges Medical University
Outcome results
None listed