Health Condition 1: N186- End stage renal disease
Conditions
Interventions
Intervention1: Lidocaine 2.5% and Prilocaine 2.5% gel: A thick layer of gel will be applied to the skin, under occlusive dressing on the arteriovenous fistula hand where the needles will be inserted,
Sponsors
Manipal College of Health Professions
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients on hemodialysis through an arteriovenous fistula. Greater than three months of maintenance hemodialysis. Those who rate their pain as mild, moderate or severe on AVF cannulation pain (as measured by VAS) during screening.
Exclusion criteria
Exclusion criteria: Hemodialysis patients with AVG as their permanent vascular access and patients with temporary access like catheters. Hemodynamically unstable patients. Skin infections or skin lesions or open wounds or ulcers. Diminished mental capacity or not able to communicate. Any known history of allergic reactions to lignocaine or prilocaine or any other topical anesthetics or other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in AVF cannulation pain (as measured by the Visual Analogue Scale) score from baseline.Timepoint: Day 1, Day 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety of topical Lidocaine and Prilocaine gel in AVF cannulation painTimepoint: Day 1, Day 3 | — |
Countries
India
Contacts
Public ContactDr Indu R Rao
Kasturba Medical College, MAHE, Manipal
Outcome results
None listed