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Clinical evaluation of Cissus Quadrangularis as a bone forming agent in implant patients- An In vivo study

A randomized clinical trail investigating the impact of Cissus Quadrangularis on the bone formation in Implant patients, using radiovisiography and measuring serum alkaline phosphatase levels at pretreatment, immediately post treatment, 1 month and 3 months intervals- A parallel group study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073507
Enrollment
20
Registered
2024-09-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K063- Horizontal alveolar bone loss

Interventions

Intervention1: Ciss Q: cissus quadrangularis, 500 mg , once daily orally, tablet form for 45 days Control Intervention1: vitamin b complex: vitamin b complex(placebo) tablet, orally , once daily for 4

Sponsors

YCMM and RDFs Dental College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients included will be age above 18 years irrespective of gender without systemic disease. 2. Patients with conventional implants placed in upper and lower posterior teeth region will be included

Exclusion criteria

Exclusion criteria: 1. Patients on steroidal therapy or immune-suppressants and suffering from any other chronic debilitating disease, infected tooth, and smoker will be excluded. 2. Patients with immediately placement of implant will be excluded from the study. 3. Patients with fracture cases will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
increased bone formation around implantTimepoint: pretreatment, immediately after implant placemnet,1 month,3months

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDR PRANJAL PATIL

YCMM and RDFs Dental College and Hospital

PANDITA.AMRITA@GMAIL.COM7300050333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026