Outcome of full pulpotomy and root canal treatment in deeply carious mature permanent teeth involving tooth pulp and periapical region.

Outcome of full pulpotomy compared to root canal treatment in cariously exposed mature permanent teeth with signs of symptomatic irreversible pulpitis and apical radiolucency: A randomized controlled trial. - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073481

Enrollment

Registered

2024-09-05

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Full(Coronal) pulpotomy.: After taking informed consent, the patients will be scheduled for treatment. Teeth will be anesthetized using 3ml 2% lignocaine hydrochloride with epinephrine

Neon Lab, New Delhi, India) given as nerve block and isolated under rubber dam. Entire carious tissue will be excavated using a large round diamond bur in airotor handpiece with water coolant and spoo

Dentsply Maillefer, Tulsa, OK). Coronal pulp tissue will be excised using a spoon excavator until the canal orifice, and hemorrhage will be controlled using damped cotton pellet moistened with 2.5% so

Dentsply Maillefer) will be placed over the chamber floor covering the pulpal floor and orifices till it is 2-4mm thick confirmed on radiograph. A damped cotton pellet will be placed and cavity will b

Eligibility

Inclusion criteria

Inclusion criteria: Healthy adult patients with extremely deep carious first and second mature permanent molars will be included. Teeth should have symtoms of symptomatic irreversible pulpitis and respond positively to pulp vitality tests. Radiograph showing apical radiolucency with periapical index score of less than or equal to 4.

Exclusion criteria

Exclusion criteria: Patients having systemic disease, pregnant, immunocompromised,habit of smoking. Teeth with mobility,deep periodontal pocket, swelling,sinus tract, fracture or previously initiated treatment.Third molars will be excluded. Teeth in which haemostasis will not be achieved within 10minutes with damped cotton soaked with sodium hypochlorite. Absence or inaequate bleeding from of bleeding from pulp canals suggesting progressive pulp necrosis.

Design outcomes

Primary

Measure	Time frame
Absence of clinical signs and symptoms with healing or reduction in size of apical radiolucency amonst the two groupsTimepoint: 1 year	—

Secondary

Measure	Time frame
Postoperative pain reduction using VAS scale and analgesic intake.Timepoint: During 1 week postoperatively and during followup visits.	—

Countries

India

Contacts

Public ContactDr Mohit Galani

All India Institute of Medical Sciences (AIIMS), Rajkot

drmohitgalani@gmail.com8053456519

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026