How iron and alkaline phosphatase levels change in normal denture wearers compared to those who wear dentures supported by implants

Biological Variation of Iron, Total Iron Binding Capacity & Alkaline Phosphatase in Completely Edentulous Patients Rehabilitated with Conventional Complete Denture, and Implant Supported Overdenture Patients – A Clinical Study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073478

Enrollment

Registered

2024-09-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K068- Other specified disorders of gingiva and edentulous alveolar ridge

Interventions

Intervention1: Implant supported overdentures in the mandibular arch: Implant supported overdentures in the mandibular arch at and d position and complete removable denture in the maxillary arch Cont

Eligibility

Inclusion criteria

Inclusion criteria: 1. For Dentate Patients: No missing teeth / if missing -rehabilitated with fixed prosthetics 2. Completely edentulous patients 3. No systemic diseases present 4.Adequate bone volume and quality to accommodate implants 5. Cooperative patient, willing for Implant overdenture surgical procedures, prostheticrehabilitation, and proper follow up

Exclusion criteria

Exclusion criteria: 1. Patients having known history of systemic diseases 2. Patients on iron and calcium supplements 3. Patients with history of smoking 4. Patients with insufficient bone quality and quantity and vertical inter arch space to accommodate the prosthetic component. 5. Patients who are not able to maintain their oral hygiene. 6. Patients with history of drug intake like immunosuppressive drugs, anti-coagulants and anti-cancer drugs three months prior to the study

Design outcomes

Primary

Measure	Time frame
There might be increase in serum iron, Total iron binding capicity and alkaline phosphatse in patients rehabilated with implant supported overdenture as compared to patients with conventional complete dentureTimepoint: To evaluate and compare the biological variation of iron, total iron binding capacity& alkaline phosphatase in dentate patients, completely edentulous patients rehabilitated with conventional complete denture and mandibular implant supported overdenture patients at insertion day and follow up after 3 months	—

Measure

Time frame

There might be increase in serum iron, Total iron binding capicity and alkaline phosphatse in patients rehabilated with implant supported overdenture as compared to patients with conventional complete dentureTimepoint: To evaluate and compare the biological variation of iron, total iron binding capacity& alkaline phosphatase in dentate patients, completely edentulous patients rehabilitated with conventional complete denture and mandibular implant supported overdenture patients at insertion day and follow up after 3 months

—

Secondary

Measure	Time frame
not applicableTimepoint: not applicable	—

Countries

India

Contacts

Public ContactDr Sapna Rani

Manav Rachna International Institute of Research and Studies

sapnarani.sds@mrei.ac.in08375899663

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026