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A Study to know Attenuation of Hemodynamic Stress Response To Laryngoscopy And Endotracheal Intubation With Two Different Doses of Injection Dexmedetomidine

Attenuation of Haemodynamic Responses to Laryngoscopy and Endotracheal Intubation with Intravenous Dexmedetomidine between two Doses : A Randomized Double Blind Prospective Study - NIl

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073465
Enrollment
70
Registered
2024-09-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: INJ.Dexmedetomidine: INJ.Dexmedetomidine 0.3mcg/kg intravenous diluted to 20 ml with normal saline will be given over 10 min Control Intervention1: NA: NA

Sponsors

Sapthagiri Institute Of Medical Sciences and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists Physical Status 1 Patient posted for elective surgeries under general anesthesia

Exclusion criteria

Exclusion criteria: Patient who were physically dependent on narcotics, those with a history of bronchial asthma, drug or alcohol abuse, known drug allergy to either clonidine or dexmedetomidine. Any predicted difficult airway.

Design outcomes

Primary

MeasureTime frame
HR and NIBP are more stable following laryngoscopy and intubation with Inj.Dexmedetomidine 0.5%Timepoint: parameters recorded will be HR, SBP, DBP and MAP at 1, 3 and 5 min after intubation.

Secondary

MeasureTime frame
compare the adverse effect & complication of the drug & their doses like hypotension & bradycardia.Timepoint: During drug infusion hemodynamics monitoring for 10 minutes

Countries

India

Contacts

Public ContactShruthi N S

Sapthagiri Institute of Medical Sciences and Research Centre

nikiladg@gmail.com9535243669

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026