Health Condition 1: N978- Female infertility of other origin
Conditions
Interventions
Intervention1: Injectable HMG: Group B will receive injectable HMG i/m as a step up regimen starting from 75IU/day from day 2-5 of cycle and increasing every 4-7 days till a maximum dose of upto 225 I
Sponsors
Pragya Kumari
Eligibility
Inclusion criteria
Inclusion criteria: Infertile women of decreased ovarian reserve as described by Cohen et al with one or both of the given two criteria and with a normal husband semen analysis 1 AFC less than 7 2 AMH less than 1.1ng/ml
Exclusion criteria
Exclusion criteria: 1 Blocked fallopian tubes bilaterally 2 Untreated intrauterine polyps 3 Untreated submucosal fibroids indenting the uterine cavity 4 Uterine malformations, intrauterine adhesions 5 Endocrine disorders-abnormal thyroid function, hyperprolactinemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of mean number of dominant follicles formed in women with decreased ovarian reserve following controlled ovarian stimulation with- 1. Clomiphene citrate 2. GonadotropinTimepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the following among the 2 drugs- 1.Biochemical pregnancy (as defined by positive Urine Pregnancy Test) 2. Clinical pregnancy (ultrasound documenting gestational sac formation, cardiac activity, crown rump length) 3. OHSS (Ovarian hyperstimulation syndrome) 4. Multiple pregnancy 5. MiscarriageTimepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Vidhi Chaudhary
Lady Hardinge Medical College and associated hospitals
Outcome results
None listed