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To compare the effectiveness and safety of microneedling with topical minoxidil 5 percent gel versus microneedling with topical 2 percent tofacitinib gel in alopecia areata

Comparative study of therapeutic efficacy and safety of microneedling with topical minoxidil 5 percent gel versus microneedling with topical 2 percent tofacitinib gel in alopecia areata - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/09/073424
Enrollment
40
Registered
2024-09-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L638- Other alopecia areata

Interventions

Intervention1: Microneedling with topical minoxidil 5% gel: 5% minoxidil gel (amount depending on area to be covered) will be applied on the selected patches of alopecia areata followed by microneedli

Sponsors

Dr. Harmandeep Kaur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients aged 18-50 years of age with limited patches of alopecia areata (upto 5 patches). 2.Patients who are willing to sign the written consent form prior to participation in the study.

Exclusion criteria

Exclusion criteria: 1.Patient having history of hypersensitivity to minoxidil or tofacitinib. 2.Active scalp infection. 3.Subjects with history of bleeding, platelet disorders. 4.History of uncontrolled diabetes mellitus and hypertension. 5.Pregnant and lactating females. 6.Immunocompromised patients.

Design outcomes

Primary

MeasureTime frame
1. Reduction in SALT score 2. Dermoscopic and photographic improvementTimepoint: At the starting of the treatment, at every visit and 4 weekly for next 16 weeks.

Secondary

MeasureTime frame
Safety of microneedling with topical minoxidil 5 percent gel versus microneedling with topical 2 percent tofacitinib gel using adverse drug reaction formTimepoint: At every visit & 4 weekly for next 16 weeks.

Countries

India

Contacts

Public ContactDr Harmandeep Kaur

Guru Gobind Singh medical college and Hospital, Faridkot

amarbirboparai@yahoo.com9815450502

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026