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Combination of Ketamine-Propofol versus Fentanyl-Propofol in short surgeries

Comparative Study of Propofol- Ketamine vs Propofol- Fentanyl as Procedural Sedation for Total Intravenous Anaesthesia in Adults Undergoing Short Surgical Procedures - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073406
Enrollment
60
Registered
2024-09-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Combination of Propofol and Ketamine versus Propofol and Fentanyl in TIVA: Patients will be anaesthetized for short surgical procedures (less than 30 minutes) either under the the comb

Sponsors

Pandit Deendayal Upadhyay Government Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - All patients with normal airway (MPG 1&2) - Study subjects classified as American Society of Anesthesiologists (grade I or II) - All subjects scheduled for elective operations requiring general anesthesia and duration of surgery less than 40mins)

Exclusion criteria

Exclusion criteria: - Emergency Surgeries - Patients allergic to eggs or soyproducts - Patients with known or unanticipated difficult intubations - Those with heart rhythms other than sinus - Those with known allergy to study drugs.

Design outcomes

Primary

MeasureTime frame
1) Demographic Data (Age and Sex) 2) Intraoperative Monitoring of Hemodynamic Variability (Pulse Rate, SBP, DBP, Respiratory Rate, Spo2(%) 3) Intraoperative Sedation Level using BIS monitor 4) Post-Operative Ramsay Sedation Score 5) Time to Recovery (Modified Aldrete Score) 6) Post- operative Side Effects Timepoint: Initially, after 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes, 1 hr, 2hr, 4hr, 8hr, 12hr, 16hr, 20hr, 24hr

Secondary

MeasureTime frame
Overall patient satisfaction post-procedureTimepoint: Immediate post-operatively, 4hrs, 8hrs, 1whrs, 16hrs, 20hrs, 24hrs

Countries

India

Contacts

Public ContactDr Vandana Parmar

Pandit Deendayal Upadhyay Government Medical College

drvandanapithadia@yahoo.com9898090220

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026