Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sugammadex: Patients will receive sugammadex 2 mg/kg at the end of Surgery
Control Intervention1: Neostigmine: Patients will receive neostigmine 0.05mg/kg and 0.01mg/kg glycopyrrolate a
Sponsors
Dayanand Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for microlaryngeal surgeries. 2. Age - 18 to 65 years. 3. American Society of Anaesthesiologists (ASA) Physical Status Grade I-III 4. Either gender
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. BMI more than 35kg/m2 3. History of allergy to drugs used in study 4. Patient with severe liver (Child Pugh B or C class), renal (stage 4 kidney disease or higher), cardiac disease and/or rhythm disorder 5. Patient requiring postoperative reintubation, tracheostomy or mechanical ventilation. 6. Known or suspected neuromuscular disease 7. Patientââ?¬•s refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in diaphragm excursion from baseline (before induction of anaesthesia) to postextubation in both the groups.Timepoint: Post extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 The change in diaphragm excursion from baseline to at 30 minutes in PACU in both the groups 2 The change in thickening fraction of internal oblique from baseline to post extubation & at 30 minutes in PACU in both the groups 3 The number of patients in whom diaphragm excursion & thickening fraction of internal oblique recovered to baseline level at post extubation & at 30 minutes in PACU in both the groupsTimepoint: Before Induction, Post extubation & at 30 min in PACU | — |
Countries
India
Contacts
Public ContactDr Chaahat Sharma
Department of Anaesthesia
Outcome results
None listed