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Effect of bundle of interventions on atelectasis in elderly undergoing general anesthesia

Comparison of a bundle of interventions with existing practices to reduce anesthesia induced atelectasis in elderly undergoing general anesthesia for non-cardiac surgeries – A double blind, randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/09/073311
Enrollment
130
Registered
2024-09-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Bundle Group: Preoxygenation in a 25degree head-up position with an FiO2 of 50% on volume controlled ventilation with a tidal volume of 8 ml/kg and a PEEP of 5 cm H2O. Then patients wil

Sponsors

AIIMS Bhubaneswar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted to surgeries under general anesthesia with duration of surgeries more than or equal to 2 hours belonging to ASA I - III including elective and emergency operations, as well as both laparoscopic and open surgical techniques.

Exclusion criteria

Exclusion criteria: Patient refusal to give consent, patients with BMI more than or equal to 30 kg/m2, with pre-existing lung disease / chest trauma, patients posted for cardiothoracic/lung surgeries, patient not getting extubated within 24 hours of surgery in ICU, Pregnant woman, patients with progressive neuromuscular weakness, chronically bed-ridden, patients posted for redo surgeries.

Design outcomes

Primary

MeasureTime frame
To compare the incidence of anesthesia induced atelectasis in both groups after surgery using lung aeration score of score more than or equal to 2 by lung ultrasonographyTimepoint: Before induction of anesthesia and after 1 hour of surgery and within 24 hours if patient shifted to ICU intubated

Secondary

MeasureTime frame
To compare the effect of predefined causes for anesthesia induced atelectasis such as age, PEEP, position of surgery, etc.Timepoint: Intraoperative;To compare the incidence of anesthesia induced atelectasis in Laparoscopic & Open surgeriesTimepoint: Before induction of anesthesia and after 1 hour of surgery and within 24 hours if patient shifted to ICU intubated;To compare the incidence of postoperative pulmonary complicationsTimepoint: Seven days postoperatively or till the day of discharge

Countries

India

Contacts

Public ContactDr Avinash R Naik

AIIMS Bhubaneswar

anaes_bhaskar@aiimsbhubaneswar.edu.in8926251076

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026