Use of Pomegranate fruit Gel in addition to teeth cleaning to cure severe gum diseases

Evaluation of clinical efficacy of Punica granatum epicarp extract, seed and whole fruit juice concentrate loaded thermo-reversible hydrogel as local drug delivery system in the treatment of Stage I and Stage II Periodontitis - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073289

Enrollment

Registered

2024-09-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Punica granatum epicarp extract loaded thermo-reversible hydrogel: Punica granatum epicarp extract loaded thermo-reversible hydrogel is given as a local drug delivery agent, which is pl

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with Stage I and Stage II Periodontitis. 2.Patients within the age group of 35 to 44 years of age for both genders. 3.Subjects with no history of allergies to the components used in the study 4.Apparently healthy individuals

Exclusion criteria

Exclusion criteria: 1.Patients with habits like any form of tobacco or alcohol consumption. 2.Systemically compromised patients 3.Pregnant women or lactating mothers 4.Patients who are on medication that influences periodontal health. 5.Patients with impacted teeth, non-functional teeth or prosthetic restorations 6.Patients who will not be able to be attend for follow up visits

Design outcomes

Primary

Measure	Time frame
1. Improvement in clinical attachment level 2.Reduction of Periodontal Pocket Probing DepthTimepoint: baseline, 1 month and 3 months	—

Secondary

Measure	Time frame
better wound healing (PISA index)Timepoint: baseline,1 month and 3 months	—

Countries

India

Contacts

Public ContactDr Boyapati Ramanarayana

SIBAR INSTITUTE OF DENTAL SCIENCES

dr.ramanarayana@gmail.com9490144365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026