Comparison of effects oxygen supplementation at different flow rates during diagnostic flexible bronchoscopy

Comparison of effects of 6L/minute oxygen supplementation versus 3L/minute oxygen supplementation during diagnostic flexible bronchoscopy - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073188

Enrollment

Registered

2024-09-02

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J18- Pneumonia, unspecified organism

Interventions

Intervention1: Supplemental oxygen at 3L/minute (group B): Patients will be randomized to two groups using block randomization technique in two groups A and B. Sedation will be given using injection m

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients above the age of 18 years requiring diagnostic flexible bronchoscopy 2. Flexible bronchoscopy done through transnasal route

Exclusion criteria

Exclusion criteria: 1)Chronic lung disease 2)Oxygen saturation (SpO2) of equal or less than 95% as measured by a pulse oximeter at baseline(current visit) 3)Any requirement for supplemental oxygen in the past 4)Patients with known or suspected allergy to midazolam or Lignocaine 5)Flexible bronchoscopy done through endotracheal or tracheostomy tube or trans-oral route 6)Patients on respiratory depressant medications 7)Patients with diagnosed heart disease 8)Hemodynamically unstable patients 9)Pregnancy and lactation 10)Patients not willing for the study

Design outcomes

Primary

Measure	Time frame
1. Mean SpO2 during flexible bronchoscopy 2. Trough SpO2 during flexible bronchoscopyTimepoint: during the procedure- Spo2- after every minute	—

Secondary

Measure	Time frame
1.Respiratory variables A)Significant oxygen desaturation event (SpO2 below 90% or more than 4% fall of SpO2 from baseline for more than one minute during the procedure) B)Respiratory rate at various time points 2.Hemodynamic variables Heart rate, Systolic blood pressure (SBP), Diastolic blood pressure (DBP) at various time points, occurrence of any arrhythmia 3.Need for FiO2 of approximately 0.9-1.0 to continue the procedure 4.Termination of the procedure due to persistent desaturation in spite of switching to FiO2 of approximately 0.9-1.0 5.Duration of oxygen supplementation requirement after flexible bronchoscopy 6.Total volume of oxygen consumed 7.Ease of bronchoscopy procedure Timepoint: during the procedure- blood pressure- after every 4 minutes respiratory rate- after every 4 minutes heart rate- after every 2 minutes	—

Measure

Time frame

1.Respiratory variables A)Significant oxygen desaturation event (SpO2 below 90% or more than 4% fall of SpO2 from baseline for more than one minute during the procedure) B)Respiratory rate at various time points 2.Hemodynamic variables Heart rate, Systolic blood pressure (SBP), Diastolic blood pressure (DBP) at various time points, occurrence of any arrhythmia 3.Need for FiO2 of approximately 0.9-1.0 to continue the procedure 4.Termination of the procedure due to persistent desaturation in spite of switching to FiO2 of approximately 0.9-1.0 5.Duration of oxygen supplementation requirement after flexible bronchoscopy 6.Total volume of oxygen consumed 7.Ease of bronchoscopy procedure Timepoint: during the procedure- blood pressure- after every 4 minutes respiratory rate- after every 4 minutes heart rate- after every 2 minutes

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Countries

India

Contacts

Public ContactDr Manu Mohan K

Kasturba Medical College, MAHE, Manipal

rahul.magazine@manipal.edu9901727204

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026