Comparing two different routes of administrating seizure drugs in children and check their efficacy and time of action

Comparison between intranasal midazolam and intravenous midazolam in children with seizures (randomised controlled study) - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/09/073174

Enrollment

164

Registered

2024-09-02

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F910- Conduct disorder confined to family context Health Condition 2: G969- Disorder of central nervous system, unspecified

Interventions

Intervention1: INTRANASAL MIDAZOLAM VS INTRAVENOUS MIDAZOLAM: Intra nasal midazolam ( Route-Intranasal) (Dose-0.2 mg/kg/dose),assessment - 3 minutes,if seizure does not aborts- second of intranasal ,i

Eligibility

Inclusion criteria

Inclusion criteria: Children with acute seizure, febrile seizure, unprovoked seizure, provoked seizure,Children who are a known case of seizure disorder.

Exclusion criteria

Exclusion criteria: Children with prolonged seizure(status epilepticus), Children"s with renal diseases, Children with hypoglycemic seizures, hypocalcemic seizure, URI.

Design outcomes

Primary

Measure	Time frame
Intranasal midazolam group –repeat one more dose of Intranasal midazolam-if at all seizure does not abort the Principal Investigator should shift to Intravenous midazolam routes. Timepoint: 2 MINS	—

Secondary

Measure	Time frame
Intravenous midazolam - if seizure does not abort in first dose of Intravenous midazolam – repeat one more dose of Intravenous midazolam . If at all seizure does not abort in Intranasal group then the Principal Investigator should shift to second line Intravenous midazolam antiepileptic"sTimepoint: 4 MINS	—

Countries

India

Contacts

Public ContactDr BHARATH KUMAR T

Sri manakula vinayagar medical college and hospita

scooby_25575@yahoo.com9003468873

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026